Adenovirus Reference Material Project
Status: In early 2022, supplies were used up.
NIST, the National Institute of Standards and Technology (US Dept. of Commerce),
performed final stability testing in November 2021. View the report here.
Analytical method for determining infectious titer after long-term storage.
Adenovirus Serotype 5 stability data was updated for Month 195 in December 2017.

Important Project Documentation
Production and Characterization, Related Articles, References, Meeting Minutes, Requests for Proposals, Submitted Bids, and the Working Group Member List are all available again for your reference.

Use and Availability / Product Information
Supplies have been totally depleted due to accelerated use in the last four years. This adenoviral reference material has been used in validating internal reference materials and assays for two decades. 5,000 vials were produced in 2001 by Introgen Therapeutics, with FDA/CBER involvement. Each 0.5 mL vial contained approximately 5 x 10E11 virus particles per mL.

NIST is collecting proposals for production and seeking government grants. FDA/CBER involvement is ongoing.

Original Project Participants